Cytochrome P450 17A1 Mouse Monoclonal Antibody - RA11062

Cytochrome P450 17A1 Mouse Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11062-50, RA11062-100

Citations, Manuals and MSDS Available upon request.

Background: cytochrome P450 family 17 subfamily A member 1 (CYP17A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: WB

Species Cross-Reactivity: Human

GeneID (Human): 1586

Protein MW (KDa): 60

SWISS: P05093

Source: Mouse

Research Use Only