Cytochrome P450 1A1 Monoclonal Antibody-MB66801

Cytochrome P450 1A1 Monoclonal Antibody

Catalogue Numbers: MB66801-50, MB66801-100

Sizes: 50µl, 100µl

Product: Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: P04798

Host: Mouse

Reactivity: Human

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies. NADPH cytochrome P450 reductase is a microsomal enzyme responsible for the transfer of electrons from NADPH to cytochrome P450 enzymes during the P450 catalytic cycle. NADPH cytochrome P450 reductase is localized to the endoplasmic reticulum where it is also able to transfer electrons to heme oxygenase and cytochrome b5. NADPH cytochrome P450 reductase is structurally related to two separate flavoprotein families, ferredoxin nucleotide reductase (FNR) and flavodoxin. Electron transfer of NADPH cytochrome P450 reductase requires the binding of two flavin cofactors, FAD and FMN, to the FNR and flavodoxin domains, respectively.

Purification and Purity: This antibody is purified through a protein G column.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of Cytochrome P450 1A1 protein.

Extra Notes: Western blot analysis of Cytochrome P450 1A1 expression in Jurkat (A) whole cell lysates.

Bioworld Molecular Weight: ~ 61 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Cytochrome P450 1A1; CYPIA1; Cytochrome P450 form 6; Cytochrome P450-C; Cytochrome P450-P1

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Cytochrome P450 1A1. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified