Product Description

Cytoglobin Polyclonal Antibody

Catalogue Numbers: BS60396-50, BS60396-100

Sizes: 50µl, 100µl

Alternative Name: Histoglobin; HGb; Stellate cell activation-associated protein; CYGB; STAP

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q8WWM9

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Hemoglobin, myoglobin, neuroglobin, and cytoglobin belong to the globin family, porphyrin-containing proteins that function in oxygen transport and storage. Myoglobin contributes to intracellular oxygen storage and transcellular facilitated diffusion of oxygen in skeletal and cardiac muscle. Neuroglobin is an oxidative stress-responsive sensor for signal transduction in the brain. Hemoglobin contributes to oxygen storage and diffusion of oxygen in blood tissue. Cytoglobin (also designated histoglobin), is a ubiquitous protein that facilitates diffusion of oxygen through tissues and acts as a scavenger for nitric oxide or other reactive oxygen species. It binds O2 via its heme and also has a protective function during oxidative stress. Cytoglobin, a hexacoordinate hemoglobin, shares less than 30% identity with other human hemoglobins and is widely expressed in a wide array of tissues including fibroblasts and nerve cell populations.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Cytoglobin polyclonal antibody detects endogenous levels of Cytoglobin protein.

Bioworld Molecular Weight: ~ 21 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Cytoglobin polyclonal antibody at 1:500 dilution
Lane 1: HEK293T cell lysate
Lane 2: Raw264.7 cell lysate
Lane 3: PC12 cell lysate

Immunogen: A synthetic peptide corresponding to residues in Human Cytoglobin.

Conjugate: Unconjugated

Modification: Unmodified