Cytokeratin 17 (8C6) Monoclonal Antibody-MB3185

Cytokeratin 17 (8C6) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3185-50, MB3185-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q04695

Host: Mouse

Reactivity: Human

Applications: WB, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: Calculated MW: 48 kDa; Observed MW: 48 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry analysis of paraffin-embedded Human liver tissue using Cytokeratin 17 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Negative control was used by secondary antibody only., Immunofluorescence analysis of Cytokeratin 17 in Human breast tissue using CK17 antibody, and DAPI., Western blot analysis of Cytokeratin 17 in Hela, MCF-7, 293T lysates using Cytokeratin 17 antibody, Immunoprecipitation analysis of Cytokeratin 17 in Hela lysates using Cytokeratin 17 antibody

Alternative Name: Keratin; type I cytoskeletal 17; Cytokeratin-17; CK-17; Keratin-17; K17

Immunogen: Synthetic Peptide of CK17

Conjugate: Unconjugated

Modification: Unmodified