Cytokeratin 18 Mouse mAb - EM1095

Cytokeratin 18 Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1095-50, EM1095-100

Citations, Manuals and MSDS Available upon request.

Background: Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.

Alternate Name: Cell proliferation inducing gene 46 protein, CK 18, CYK 18, K 18, Keratin 18, Ketatin D, KRT18

Source: Mouse

Applications: WB, IHC, IF

Dilution: WB 1:1, 000-3, 000 IF 1:100-200 IHC 1:200-500

Reactivity: Human, Rat, Mouse

Immunogen: Recombinant Protein

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 46kDa

Human Gene ID: 3875

Human SWISS Prot NO: P05783

Subcellular Location: Cytoplasm,  Intermediate filament,  Keratin,  Nucleus

Research Use Only