Product Description

Cytokeratin 8 (Phospho-S432) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS64523-50, BS64523-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Cytokeratin 8 belongs to the type B (basic) subfamily of high molecμlar weight keratins and exists in combination with cytokeratin 18. Cytokeratin 8 is primarily found in the non squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellμlar carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 and 18.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC, IF

Alternate Names: Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, Short name=K8, Type-II keratin Kb8, KRT8, CYK8

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: Synthetic phosphopeptide derived from human Cytokeratin 8 around the phosphorylation site of Serine 432.

Dilution: WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Cytokeratin 8 (Phospho-S432) polyclonal antibody detects endogenous levels of Cytokeratin 8 protein only when phosphorylated at Ser432.

Molecular Weight: ~ 55 kDa

Pathway: Contribution of Soluble Factors to EMT,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P05787

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only