Cytokeratin 9 Polyclonal Antibody-BS90390

Cytokeratin 9 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90390-50, BS90390-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P35527(Human) Q6RHW0(Mouse) Q8CIS9(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IP

All Applications: WB:1:500-1:1,000
IHC:1:50-1:200

Background: Cytokeratins comprise a diverse group of intermediate filament proteins that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratin 9 is an unusually large, type I acidic cytokeratin that differentiates human plantar and palmar epidermal cells. Cytokeratin 9 localizes to the suprabasal layers as well as the upper epidermal layers such as the glandular ridges and interridges. The domains of cytokeratin 9 include a head, an α-helical coiled-coil-forming rod, and a tail; cytokeratin 9 shares significant homology with cytokeratin 10. Mutations in the cytokeratin 9 gene correlate with the development of epidermolytic palmoplantar keratoderma (EPPK), an autosomal dominant inherited skin disorder that is characterized by hyperkeratosis of the skin over the palms and soles.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-Cytokeratin 9 antibody. Counter stained with hematoxylin.

Bioworld Molecular Weight: 62 kDa

Specificity: Cytokeratin 9 polyclonal antibody detects endogenous levels of Cytokeratin 9 protein.

Alternative Name: CK-9, K9, KRT9, CK 9, CK-9, Cytokeratin 9, Cytokeratin-9, Cytokeratin9, EPPK, K1C9, K9, Keratin 9, Keratin, Keratin type I cytoskeletal 9, Keratin-9, Keratin9, KRT 9, Krt9, Spermatid Perinuclear Ring Manchette Protein K9, type I cytoskeletal 9,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified