D2HGDH Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A16213-20, A16213-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 56kDa
Observed Molecular Weight: 56kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 728294
SWISS: Q8N465
Alternate Names: D2HGD; D2HGDH
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Endocrine Metabolism.
NCBI Alias: D2HGDH
Research Use Only