D4DR rabbit pAb - ES2137

D4DR rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2137-50, ES2137-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008],

Alternate Name: DRD4; D (4) dopamine receptor; D (2C) dopamine receptor; Dopamine D4 receptor

Source: Rabbit

Applications: WB; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human DRD4. AA range:355-404

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 48kD

Human Gene ID: 1815

Human SWISS Prot NO: P21917

Subcellular Location: Cell membrane; Multi-pass membrane protein.

Research Use Only