DAAM1 Polyclonal Antibody - E-AB-13182

DAAM1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-13182-60, E-AB-13182-120, E-AB-13182-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: DAAM1

Target Synonym: DAAM 1; Dishevelled associated activator of morphogenesis 1; FLJ41657; KIAA0666

Research Areas: Signal Transduction, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9Y4D1

Background: Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex.

Concentration: 1.2 mg/mL

Immunogen: Synthetic peptide of human DAAM1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Calculated MW: 123kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only