Product Description

DAAM1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24070-50, RA24070-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: dishevelled associated activator of morphogenesis 1 (DAAM1) Homo sapiens Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: Disheveled-associated activator of morphogenesis 1

Clonality: Polyclonal

Dilution: WB 1:500-2000, ELISA 1:10000-20000

Molecular Weight: 123

Protein Molecular Weight (kDa): 123

Storage: -20°C/1 year

Human Gene ID: 23002

Human SwissProt Number: Q9Y4D1

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only