Dab1 rabbit pAb - ES2139

Dab1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2139-50, ES2139-100

Citations, Manuals and MSDS Available upon request.

Background: The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008],

Alternate Name: DAB1; Disabled homolog 1

Source: Rabbit

Applications: WB; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Dab1. AA range:199-248

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 60kD

Human Gene ID: 1600

Human SWISS Prot NO: O75553

Subcellular Location: nucleolus, microtubule organizing center, cytosol, brush border, postsynaptic density, membrane, neuron projection, neuronal cell body, intracellular membrane-bounded organelle, apical part of cell, perinuclear region of cytoplasm,

Research Use Only