Product Description

DAB2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65935-50, BS65935-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regμlated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modμlate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig

Host: Rabbit

Applications: FCM

Alternate Names: DAB 2, DAB2, DAB2_HUMAN； Differentially expressed protein 2, Disabled (Drosophila) homolog 2 (mitogen responsive phosphoprotein), disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein), Disabled homolog 2, Disabled homolog 2 mitogen responsive phosphoprotein (Drosophila), Disabled homolog 2 mitogen responsive phosphoprotein, disabled homolog 2 mitogen-responsive phosphoprotein (Drosophila), DOC 2, DOC2, FLJ26626, Mitogen responsive phosphoprotein.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human DAB2:31-130/770

Dilution: Flow-Cyt=1ug/Test

Purification: affinity purified by Protein A

Specificity: DAB2 Polyclonal Antibody detects endogenous levels of DAB2 protein.

Molecular Weight: 82kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P98082

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only