DAD1 rabbit pAb - ES17025

DAD1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES17025-50, ES17025-100

Citations, Manuals and MSDS Available upon request.

Background: DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human DAD1 AA range: 38-88

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 1603

Human SWISS Prot NO: P61803

Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein.

Research Use Only