Product Description

DAPK2 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10812-50, MB10812-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9UIK4

Host: Rabbit

Reactivity: Rat

Applications: WB,IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation (PubMed:17347302). Regulates granulocytic motility by controlling cell spreading and polarization (PubMed:24163421).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of DAPK2 in rat spleenLysates using DAPK2 antibody.

Bioworld Molecular Weight: Calculated MW: 43 kDa; Observed MW: 43 kDa

Specificity: IgG

Alternative Name: DAPK2; Death-associated protein kinase 2; DAP kinase 2; DAP-kinase-related protein 1; DRP-1

Immunogen: A synthetic peptide of human DAPK2

Conjugate: Unconjugated

Modification: Unmodified