DARC Polyclonal Antibody
Catalogue Numbers: BS60586-50, BS60586-100
Sizes: 50µl, 100µl
Alternative Name: Atypical chemokine receptor 1; Duffy antigen/chemokine receptor; Fy glycoprotein; GpFy; Glycoprotein D; Plasmodium vivax receptor; CD234; ACKR1; DARC; FY, GPD
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q16570
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: Duffy protein (CD234) is the receptor for the human malarial parasite Plasmodium vivax, simian malarial parasite Plasmodium knowlesi, and can bind chemokines. Duffy is an acidic glycoprotein that carries antigenic determinants of the Duffy blood group system, which consists of four alleles, five phenotypes and five antigens. Duffy protein is detectable in endothelial cells of postcapillary venules, epithelial cells of kidney collecting ducts, lung alveoli, thyroid, and Purkinje cells in the cerebellum.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: DARC polyclonal antibody detects endogenous levels of DARC protein.
Bioworld Molecular Weight: ~ 36 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of DARC polyclonal antibody at 1:500 dilution
Lane 1: HEK293T whole cell lysate
Lane 2: Raw264.7 whole cell lysate
Lane 3: PC12 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human DARC
Conjugate: Unconjugated
Modification: Unmodified