DARPP-32 (phospho Thr34) rabbit pAb - ES1523

DARPP-32 (phospho Thr34) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1523-50, ES1523-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

Alternate Name: PPP1R1B; DARPP32; Protein phosphatase 1 regulatory subunit 1B; DARPP-32; Dopamine- and cAMP-regulated neuronal phosphoprotein

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human DARPP-32 around the phosphorylation site of Thr34. AA range:18-67

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 35kD

Human Gene ID: 84152

Human SWISS Prot NO: Q9UD71

Subcellular Location: Cytoplasm

Research Use Only