DBLOH rabbit pAb - ES11292

DBLOH rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11292-50, ES11292-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013],

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 26kD

Human Gene ID: 56616

Human SWISS Prot NO: Q9NR28

Subcellular Location: Mitochondrion. Released into the cytosol when cells undergo apoptosis.

Research Use Only