Product Description

DCLK1 Monoclonal Antibody

Catalogue Numbers: MB66717-50, MB66717-100

Sizes: 50µl, 100µl

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: O15075

Host: Mouse

Reactivity: Human, Mouse

Applications: WB

All Applications: WB (1/1000 - 1/2000)

Background: Doublecortin-like kinase 1 (DCLK1, DCAMKL1) is a serine/threonine kinase that belongs to the CaM kinase family and shares homology with the neuronal microtubule binding protein doublecortin. DCLK1 is thought to be involved in calcium signaling pathways controlling neuronal development in the embryonic brain. The kinase also functions in the mature nervous system and is highly expressed in regions of active neurogenesis in the neocortex and cerebellum. Research studies suggest that the DCLK1 kinase is highly expressed in subpopulations of cells within the colon and gastric epithelium and in the pancreas. The nature of these cell populations, whether normal, stem-like, or tumor-initiating, is unclear.

Purification and Purity: This antibody is purified through a protein G column.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of DCLK1 protein.

Extra Notes: Western blot analysis of DCLK1 expression in human brain (A), mouse brain (B), TT (C) whole cell lysates.

Bioworld Molecular Weight: ~ 82 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: DCAMKL1; DCDC3A; KIAA0369; Serine/threonine-protein kinase DCLK1; Doublecortin domain-containing protein 3A; Doublecortin-like and CAM kinase-like 1; Doublecortin-like kinase 1

Immunogen: Recombinant fusion protein of human DCLK1. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified