DCLRE1C Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5615-20, A5615-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a nuclear protein that is involved in V (D) J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 78kDa
Observed Molecular Weight: 90kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 64421
SWISS: Q96SD1
Alternate Names: SCIDA; SNM1C; A-SCID; RS-SCID; DCLREC1C; DCLRE1C
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, DNA Damage Repair.
NCBI Alias: DCLRE1C
Research Use Only