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DCPS Polyclonal Antibody - E-AB-65756

DCPS Polyclonal Antibody - E-AB-65756

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DCPS Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-65756-60, E-AB-65756-120, E-AB-65756-200 Citations, Manuals and MSDS Available upon request. Abbreviation: DCPS Target Synonym: DCPS; ARS; DCS1; HINT-5; HINT5; HSL1; HSPC015 Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human Application: WB Isotype: IgG Clonality: Polyclonal UNIProt ID: Q96C86 Background: This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5′ mRNA cap structure, which appear in the 3′ → 5′ mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover. Concentration: 1mg/mL Immunogen: Recombinant fusion protein of human DCPS (NP_054745.1). Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Purification Method: Affinity purification Dilution: WB 1:1000-1:2000 Calculated MW: 38kDa Observed MW: 38kDa Storage: -20°C/One year. Avoid freeze / thaw cycles. Shipping: Ice bag Research Use Only
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