DCPS Rabbit pAb - A10299

DCPS Rabbit pAb Sizes: 20μL, 100μL Catalogue Numbers: A10299-20, A10299-100 Citations, Manuals and MSDS Available upon request. Background: This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5′ mRNA cap structure, which appear in the 3′ → 5′ mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover. Category: Polyclonal Antibodies Applications: WB, ELISA Cross-reactivity: Human, Mouse Protein Weight: 39kDa Observed Molecular Weight: 38kDa Immunogen: Recombinant protein (or fragment) Species: Human GeneID: 28960 SWISS: Q96C86 Alternate Names: ARS; DCS1; HSL1; HINT5; HINT-5; HSPC015; DCPS Source: Rabbit Isotype: IgG Purity: Affinity purification Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3. Recommended Dilutions: WB, 1:1000 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. Research Areas: Epigenetics Nuclear Signaling. NCBI Alias: DCPS Research Use Only