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DCTN3 Rabbit Polyclonal Antibody - RA31941

DCTN3 Rabbit Polyclonal Antibody - RA31941

Regular price $336.00 CAD
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DCTN3 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31941-50, RA31941-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000

Applications: WB

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 11258

SWISS: O75935

Source: Rabbit

Research Use Only

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