Product Description

DDB2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31944-50, RA31944-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: damage specific DNA binding protein 2 (DDB2) Homo sapiens This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 46

Protein Molecular Weight (kDa): 46

Storage: -20°C/1 year

Human Gene ID: 1643

Human SwissProt Number: Q92466

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only