DDC Polyclonal Antibody - E-AB-53391

DDC Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53391-60, E-AB-53391-120, E-AB-53391-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: DDC

Target Synonym: AADC; Aromatic L Amino Acid Decarboxylase; Aromatic-L-amino-acid decarboxylase; DDC; DDC_HUMAN; DOPA decarboxylase (aromatic L-amino acid decarboxylase); DOPA decarboxylase

Research Areas: Neuroscience,Cancer,Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P20711

Background: The encoded protein catalyzes the decarboxylation of L-3, 4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Concentration: 0.8 mg/mL

Immunogen: Synthetic peptide of human DDC

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:1000-1:5000, ELISA 1:5000-1:10000

Calculated MW: 54 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only