DDR2 Polyclonal Antibody Sizes: 50μl, 100μl Catalogue Numbers: BS70578-50, BS70578-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regμlates cell differentiation, remodeling of the extracellμlar matrix, cell migration and cell proliferation. Required for normal bone development. Regμlates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regμlates remodeling of the extracellμlar matrix by up-regμlation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing. Category: Primary Antibody Reactivity: Human, Mouse, Rat Host: Rabbit Applications: WB, ELISA Alternate Names: CD_antigen: CD167b, NTRKR3, TKT, TYRO10, Discoidin domain-containing receptor 2 Clonality: Polyclonal Conjugate: Unconjugated Modification: Unmodification Immunogen: KLH conjugated synthetic peptide derived from human CD167b: 245-350/855 Dilution: WB 1:500 - 1:2000 ELISA 1:5000-1:10000 Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). Specificity: DDR2 polyclonal antibody detects endogenous levels of DDR2 protein. Molecular Weight: ~ 92 kDa Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. SwissProt: Q16832 Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Research Use Only