DDR2 Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS70578-50, BS70578-100 Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Swiss-Prot: Q16832 Host: Rabbit Reactivity: Human, Mouse, Rat Applications: WB, ELISA All Applications: WB 1:500 - 1:2000 ELISA 1:5000-1:10000 Background: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing. Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity: DDR2 polyclonal antibody detects endogenous levels of DDR2 protein. Bioworld Molecular Weight: ~ 92 kDa Note: For research use only, not for use in diagnostic procedure. Alternative Name: CD_antigen: CD167b; NTRKR3; TKT; TYRO10; Discoidin domain-containing receptor 2 Immunogen: KLH conjugated synthetic peptide derived from human CD167b: 245-350/855 Conjugate: Unconjugated Modification: Unmodified