Product Description

DDX11 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS70852-50, BS70852-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q96FC9

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB 1:500 - 1:2000

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. This gene is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: DDX11 polyclonal antibody detects endogenous levels of DDX11 protein.

Bioworld Molecular Weight: ~ 108 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of extracts of various cells, using DDX11 antibody.

Alternative Name: CHL1-related protein 1; hCHLR1; DEAD/H box protein 11; KRG-2; DDX11; CHL1; CHLR1; KRG2

Immunogen: Recombinant protein of human DDX11.

Conjugate: Unconjugated

Modification: Unmodified