DDX24 Polyclonal Antibody
Catalogue Numbers: BS61138-50, BS61138-100
Sizes: 50µl, 100µl
Alternative Name: ATP-dependent RNA helicase DDX24 (EC:3.6.4.13); DEAD box protein 24; DDX24
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9GZR7
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX24 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 24) is an 859 amino acid protein that contains one helicase C-terminal domain and one helicase ATP-binding domain. Expressed ubiquitously with highest levels in brain and heart, DDX24 functions as an ATP-dependent RNA helicase that is subject to DNA damage-dependent phosphorylation. Human DDX24 shares 79% sequence similarity with its mouse counterpart, suggesting a conserved role between species.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: DDX24 polyclonal antibody detects endogenous levels of DDX24 protein.
Bioworld Molecular Weight: ~ 90 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of DDX24 polyclonal antibody at 1:500 dilution
Line1:A549 whole cell lysate
Line2:PC12 whole cell lysate
Line3:sp20 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human DDX24.
Conjugate: Unconjugated
Modification: Unmodified