DDX3 Mouse Monoclonal Antibody - RA11088

DDX3 Mouse Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11088-50, RA11088-100

Citations, Manuals and MSDS Available upon request.

Background: DEAD-box helicase 3, X-linked (DDX3X) Homo sapiens The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarit

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: WB; IP; ICC

Species Cross-Reactivity: Human; Rat; MouseMonkey

GeneID (Human): 1654

Protein MW (KDa): 75

SWISS: O00571

Source: Mouse

Research Use Only