Product Description

Dectin-2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24162-50, RA24162-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: C-type lectin domain family 6 member A (CLEC6A) Homo sapiens The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, IHC-p, IF (paraffin section), ELISA

Alternate Names: CLEC6A, CLECSF10, DECTIN2, C-type lectin domain family 6 member A, C-type lectin superfamily member 10, Dendritic cell-associated C-type lectin 2, DC-associated C-type lectin 2, Dectin-2

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight: 23

Protein Molecular Weight (kDa): 23

Storage: -20°C/1 year

Human Gene ID: 93978

Human SwissProt Number: Q6EIG7

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only