DEF6 rabbit pAb - ES11449

DEF6 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11449-50, ES11449-100

Citations, Manuals and MSDS Available upon request.

Background: defensin alpha 6 (DEFA6) Homo sapiens Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel. [provided by RefSeq, Oct 2014],

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human protein . at AA range: 51-100

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 11kD

Human Gene ID: 1671

Human SWISS Prot NO: Q01524

Subcellular Location: Secreted. Cytoplasmic vesicle, secretory vesicle. Stored as propeptide in secretory granules of small intestinal Paneth cells and found in the ileum lumen as mature peptide.

Research Use Only