Product Description

DEFB1 Polyclonal Antibody

Catalogue Numbers: BS60361-50, BS60361-100

Sizes: 50µl, 100µl

Alternative Name: Beta-defensin 1; BD-1; hBD-1; Defensin, beta 1; DEFB1; BD1, HBD1; β-defensin 1; Defensin β-1; Defensin β1;

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P60022

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: β-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, β-defensins are developmentally regulated. Research indicates that human β-defensin 1 may contribute to the antimicrobial activity of airway surface fluid and may play a role in the mucosal defenses of the lung. Human β-defensin 1 shares homology with other β-defensins from human blood filtrate and is also present in nanomolar concentrations in human plasma. In addition to the antimicrobial activity of human airway epithelia, β-defensin 1 may play a role in the mucosal defenses of the lung.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: DEFB1 polyclonal antibody detects endogenous levels of DEFB1 protein.

Bioworld Molecular Weight: ~ 7 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of DEFB1 polyclonal antibody at 1:500 dilution
Lane 1: HEK293T whole cell lysate
Lane 2: Mouse liver tissue lysate
Lane 3: Rat heart tissue lysate

Immunogen: A synthetic peptide corresponding to residues in Human DEFB1.

Conjugate: Unconjugated

Modification: Unmodified