Product Description

DEFB4 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS7188-50, BS7188-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: β-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, β-defensins are developmentally regμlated. Unlike the other previously described human β-defensins, human β-defensin 4 (hBD-4) expression is restricted to a few tissues, with highest expression in testis. A restricted pattern is also exhibited by mouse β-defensin 4. Rat β-defensin 4 (also desiganated BD-4, RBD-4, BD-2, and RBD-2) is developmentally regμlated in the lung and is predominantly expressed in the lung and, to a lesser extent, in the trachea and tongue. It exhibits a regμlation pattern similar to that of specific genes involved in host defense around the time of birth. The selectivity in both expression pattern and antimicrobial activity of human β-defensin 4 suggests that it is best suited to act at the epithelial locations where it is expressed.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF

Alternate Names: Beta-defensin 4A, Beta-defensin 2, BD-2, hBD-2, Defensin beta 2, Skin-antimicrobial peptide 1, SAP1, DEFB4A, DEFB102, DEFB2, DEFB4, DEFB4B, β-defensin 4A, Defensin-β2, Defensin β2

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human DEFB4.

Dilution: WB: 1:500~1:2000
IHC: 1:50~1:200
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: DEFB4 polyclonal antibody detects endogenous levels of DEFB4 protein.

Molecular Weight: ~ 8 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O15263

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only