DEN1B rabbit pAb - ES16970

DEN1B rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES16970-50, ES16970-100

Citations, Manuals and MSDS Available upon request.

Background: Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human DEN1B AA range: 325-375

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 163486

Human SWISS Prot NO: Q6P3S1

Subcellular Location: Cytoplasm, cytosol. Cytoplasmic vesicle, clathrin-coated vesicle.

Research Use Only