DEN1B Rabbit Polyclonal Antibody - RA24171

DEN1B Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24171-50, RA24171-100

Citations, Manuals and MSDS Available upon request.

Background: Clathrin (see MIM 118955) -mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024) . Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]) .[supplied by OMIM, Nov 2010],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1：500-2000

Applications: WB

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 163486

SWISS: Q6P3S1

Source: Rabbit

Research Use Only