DEP1 Polyclonal Antibody Sizes: 50μl, 100μl Catalogue Numbers: BS65603-50, BS65603-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecμles that regμlate a variety of cellμlar processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellμlar region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regμlate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Mμltiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Category: Primary Antibody Reactivity: Human, Mouse, Rat, Rabbit Host: Rabbit Applications: WB Alternate Names: CD 148, CD148, CD148 antigen, Density enhanced phosphatase 1, Density-enhanced phosphatase 1, DEP 1, DEP-1, HPTP eta, HPTPeta, Human density enhanced phosphatase 1, Protein tyrosine phosphatase eta, Protein tyrosine phosphatase receptor type J, Protein tyrosine phosphatase receptor type J polypeptide, Protein-tyrosine phosphatase eta, Protein-tyrosine phosphatase receptor type J, PTPJ, Ptprj, PTPRJ_HUMAN, R PTP Eta, R-PTP-eta, R-PTP-J, Receptor type tyrosine protein phosphatase eta, Receptor-type tyrosine-protein phosphatase eta, SCC 1, SCC1.   Clonality: Polyclonal Conjugate: Unconjugated Modification: Unmodification Immunogen: KLH conjugated synthetic peptide derived from human PTPRJ:865-970/1337  Dilution: WB=1:500-2000  Purification: affinity purified by Protein A Specificity: DEP1 Polyclonal Antibody detects endogenous levels of DEP1 protein. Molecular Weight: 60 kD Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. SwissProt: Q12913 Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Research Use Only