DERL1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA31963-50, RA31963-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: derlin 1 (DERL1) Homo sapiens The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012], Reactivity: Human, Mouse Host: Rabbit Applications: WB, ELISA Clonality: Polyclonal Dilution: WB 1:500-2000 ELISA 1:5000-20000 Molecular Weight: 27 Protein Molecular Weight (kDa): 27 Storage: -20°C/1 year Human Gene ID: 79139 Human SwissProt Number: Q9BUN8 Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Research Use Only