Desmin (V56) Polyclonal Antibody-BS1860

Desmin (V56) Polyclonal Antibody

Catalogue Numbers: BS1860-50, BS1860-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P17661

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB IHC

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200

Background: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. Intermediate filaments are constructed from two-chain alpha-helical coiled-coil molecules arranged on an imperfect helical lattice and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. One such intermediate filament protein, Vimentin, is a general marker of cells originating in the mesenchyme. Vimentin is frequently co-expressed with other members of the intermediate filament family such as the cytokeratins,in neoplasms including melanoma and breast carcinoma. Vimentin and Desmin, a related class III intermediate filament, are both expressed during skeletal muscle development.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Desmin (V56) polyclonal antibody detects endogenous levels of Desmin protein.

Extra Notes: Western blot (WB) analysis of Desmin (V56) polyclonal antibody at 1:500 dilution
Lane1:MCF-7 cell lysate
Lane2:sp2/0 cell lysate
Lane3:PC12 cell lysate

Bioworld Molecular Weight: ~ 54 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: DES

Immunogen: Synthetic peptide, corresponding to amino acids 20-70 of Human Desmin.

Conjugate: Unconjugated

Modification: Unmodified