Product Description

Desmoglein 4 Polyclonal Antibody

Catalogue Numbers: BS60141-50, BS60141-100

Sizes: 50µl, 100µl

Alternative Name: Desmoglein-4; Desmoglein4; Cadherin family member 13; DSG4; CDHF13

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q86SJ6

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Desmoglein proteins are cadherin-type cell adhesion molecules. Desmoglein 4 (dsg4) shares 41% identity with human desmoglein 1, 37% with human desmoglein 2 and 50% with human desmoglein 3. A type I membrane protein of the cadherin protein family, dsg4 is expressed in salivary gland, suprabasal epidermis, hair follicle, testis, prostate and skin. In the hair follicle, dsg4 is an important mediator of keratinocyte cell adhesion and coordinates the transition from proliferation to differentiation. The human DSG4 gene is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 and DSG3.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Desmoglein 4 polyclonal antibody detects endogenous levels of Desmoglein 4 protein.

Bioworld Molecular Weight: ~ 114 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Desmoglein 4 polyclonal antibody at 1:500 dilution
Lane 1: HEK293T whole cell lysate
Lane 2: sp2/0 whole cell lysate
Lane 3: H9C2 whole cell lysate

Immunogen: A synthetic peptide corresponding to residues in Human Desmoglein 4.

Conjugate: Unconjugated

Modification: Unmodified