Product Description

DGCR8 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BZ16637-50, BZ16637-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DGCR8 function as a molecμlar anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ICC/IF, IP

Alternate Names: DGCR8, DGCRK6, Gy1, C22orf12, D16Wis2, pasha

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: A synthesized peptide derived from human DGCR8

Dilution: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 86 kDa, Observed MW: 100 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8WYQ5

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Research Use Only