DGCR8 Rabbit Polyclonal Antibody - BT-AP09158

DGCR8 Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09158-20, BT-AP09158-50, BT-AP09158-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein| Drosha. Alternate splicing results in multiple transcript variants.

Research Areas: Epigenetics and nuclear signaling

Target Protein: DGCR8

Applications: WB

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: DGCR8

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q8WYQ5; Mouse: Q9EQM6

Synonyms: DGCR8; Microprocessor complex subunit DGCR8; DiGeorge syndrome critical region 8)

GeneID: Human: 54487; Mouse: 94223

Research Use Only