DHSO Rabbit Polyclonal Antibody - RA31982

DHSO Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31982-50, RA31982-100

Citations, Manuals and MSDS Available upon request.

Background: Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]) . The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD (+) cofactor.[supplied by OMIM, Jul 2010],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1：500-2000 IP 1:200

Applications: WB; IP

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 6652

SWISS: Q00796

Source: Rabbit

Research Use Only