DIABLO Polyclonal Antibody - E-AB-60734

DIABLO Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-60734-60, E-AB-60734-120, E-AB-60734-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: DIABLO

Target Synonym: DIABLO; DFNA64; SMAC

Research Areas: Cancer, Cell Biology, Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9NR28

Background: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human DIABLO (NP_063940.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 21kDa/22kDa/27kDa

Observed MW: 18kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only