Dilpacimab ELISA Kit - DV571018

Dilpacimab ELISA Kit

Size: 96T

Catalogue Number: DV571018-96

Citations, Manuals and MSDS Available upon request.

Stability and Storage: The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.

Detection Method: Colorimetric

Sample Type: Plasma, Serum

Assay Type: Quantitative

Sensitivity: 0.156 μg/ml

Range: 0.31-5 μg/mL

Recovery: 80-120%

Background: Dilpacimab (formerly ABT-165), a novel dual-variable domain immunoglobulin, targets both delta-like ligand 4 (DLL4) and VEGF pathways. Here, we present safety, pharmacokinetic (PK), pharmacodynamic (PD), and preliminary efficacy data from a phase I study (trial registration ID: NCT01946074) of dilpacimab in patients with advanced solid tumors. Eligible patients (≥18 years) received dilpacimab intravenously on days 1 and 15 in 28-day cycles at escalating dose levels (range, 1.25–7.5 mg/kg) until progressive disease or unacceptable toxicity.

Shipping: 2-8 ℃

For Research Use Only.