Product Description

DiMethyl-DNMT3A-K44 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS74110-50, BS74110-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regμlated.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IF/ICC

Alternate Names: Dnmt3a, MmuIIIA, DNMT3A2, M.HsaIIIA, TBRS

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Methylated

Immunogen: A synthetic dimethylated peptide around K44 of mouse DNMT3A(NP_031898.1).

Dilution: IF/ICC, 1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Methylated

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O88508

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only