Product Description

DISC1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-12369-60, E-AB-12369-120, E-AB-12369-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: DISC1

Target Synonym: C1orf136; DISC1; DISC1; Disrupted in schizophrenia 1; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9

Research Areas: Cancer, Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9NRI5

Background: This gene encodes a protein with multiple coiled coil motifs which is located in the Nucleus, Cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Concentration: 0.4 mg/mL

Immunogen: Synthetic peptide of human DISC1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only