Product Description

DKK3 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS62351-50, BS62351-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Dickkopf-related protein 3, antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regμlated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adμlt, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Dickkopf-related protein 3, Dickkopf-3, Dkk-3, hDkk-3, DKK3, REIC, UNQ258, PRO295

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to Human DKK3.

Dilution: WB:1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: DKK3 polyclonal antibody detects endogenous levels of DKK3 protein.

Molecular Weight: ~ 55 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9UBP4

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only