DLL4 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90415-50, BS90415-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9NR61(Human) D3ZHH1(Rat)
Host: Rabbit
Reactivity: Human, Rat
Applications: WB, ICC IHC FC
All Applications: WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Background: The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged, Jagged-2 and Delta. While blocking the differentiation of progenitor cells into the B-cell lineage, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics. The protein is a membrane protein expressed in heart, pancreas, brain and muscle during gastrulation and early organogenesis and in adult heart and lung. Delta-4 is a membrane protein that activates Notch-1 and Notch-4. It is expressed in a wide range of adult and fetal tissues, especially in vascular endothelium.
Purification and Purity: Peptide affinity purified.
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: DLL4 polyclonal antibody detects endogenous levels of DLL4 protein.
Bioworld Molecular Weight: 74 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of DLL4 on human lung tissue lysate using anti-DLL4 antibody at 1/500 dilution., ICC staining DLL4 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: Delta4, DLL4, UNQ1895/PRO4341, AOS6, Delta 4, delta 4 precursor, Delta ligand 4, delta ligand 4 precursor, Delta like 4, Delta like 4 homolog, Delta like 4 protein, Delta like canonical Notch ligand 4, Delta like protein 4, Delta-like 4 (Drosophila), Delta-like protein 4, Delta4, DLL 4, Dll4, DLL4, Drosophila Delta homolog 4, hdelta2, Homeobox protein DLL-4, MGC126344, Notch ligand delta 2, Notch ligand DLL4, Notch ligand DLL4 precursor, XDLL-4,
Immunogen: Peptide.
Conjugate: Unconjugated
Modification: Unmodified