Product Description

DMA Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32014-50, RA32014-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: major histocompatibility complex, class II, DM alpha (HLA-DMA) Homo sapiens HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 28

Protein Molecular Weight (kDa): 28

Storage: -20°C/1 year

Human SwissProt Number: P28067

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only