Product Description

DMBT1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-40467-60, E-AB-40467-120, E-AB-40467-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: DMBT1

Target Synonym: Apactin; CRP; Crpd; DBMT1; Deleted in malignant brain tumors 1 protein; DMBT1; DMBT1 prototype precursor; Ebnerin; FLJ61058; Glycoprotein 300; Glycoprotein 340; GP340; Gp340 variant protein; GP340; Hensin; MGC164738; Muclin; p80; Pancrin; SAG; Salivary agglutinin; Surfactant pulmonary associated D binding protein; Vomeroglandin

Research Areas: Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9UGM3

Background: Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system.

Concentration: 0.71mg/mL

Immunogen: Recombinant Human Deleted in malignant brain tumors 1 protein

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.

Purification Method: Antigen Affinity Purification

Dilution: IHC 1:200-1:500

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only